Uses of Intravenous Lidocaine
Radius Anesthesia
MARCH 25, 2024
Lidocaine is an amide local anesthetic commonly used for local or topical anesthesia. As with other local anesthetics, lidocaine’s mechanism of action occurs at sodium ion channels on the internal surface of the plasma membranes of neurons. By ionizing via the hydrogen ions present in the axoplasm, the initially uncharged molecule becomes a cation that can bind reversibly to the sodium channels while they are in their “open” state, preventing depolarization and, consequently, signaling.
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