Cardiac and General Anesthesiology

APRIL 6, 2023

First-generation cephalosporins are a class of antibiotics that have been used for over 50 years to treat a variety of bacterial infections. They are structurally similar to penicillins and have a similar mechanism of action, inhibiting bacterial cell wall synthesis. As a result, they are primarily effective against gram-positive organisms. Some of the most commonly used first-generation cephalosporins include cefazolin, cephalexin, and cephalothin.

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Cardiac and General Anesthesiology

APRIL 6, 2023

Second-generation cephalosporins are a class of antibiotics that were developed in the 1970s. They are derived from the same fungus, Acremonium, as the first-generation cephalosporins. However, they have a broader spectrum of activity and are effective against both gram-positive and gram-negative organisms. Some of the most commonly used second-generation cephalosporins include cefuroxime, cefoxitin, and cefotetan.

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