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Hypernatremia and the resulting hyperosmolar state impact various bodily functions. One well-known consequence is its influence on neurological function. The occurrence of hypernatremia and subsequent hyperosmolality triggers a movement of free water from within cells to the extracellular space. This shift results in the shrinkage of brain cells, potentially leading to vascular rupture and persistent neurological impairments in severe cases.
How a group of emergency department staff at Penn Presbyterian Medical Center found an innovative project to foster equity and inclusion in the workplace.
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Neostigmine, a well-known anticholinesterase medication, has been extensively used in the medical field, particularly in the management of myasthenia gravis and as an antidote for anticholinergic poisoning. However, its influence on cognitive functions, especially in the context of early postoperative cognitive dysfunction (POCD), has become a subject of increasing interest among researchers and clinicians.
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